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5-HT3 receptor antagonists for the treatment of nausea/vomiting

   
@article{APM1037,
	author = {Howard S. Smith and Lorraine R. Cox and Eric J. Smith},
	title = {5-HT3 receptor antagonists for the treatment of nausea/vomiting},
	journal = {Annals of Palliative Medicine},
	volume = {1},
	number = {2},
	year = {2012},
	keywords = {},
	abstract = {It is well appreciated that a number of things (e.g., various insults, chemotherapeutic agents, radiation) may lead to the release of serotonin from the enterochromaffin of the gastrointestinal tract. Released serotonin may then bind to certain 5-HT3 receptors and promote nausea/vomiting. 5-HT3 receptor antagonists may ameliorate nausea/vomiting in a number of circumstances and have been utilized as important antiemetics for multiple conditions such as chemotherapy-induced nausea/vomiting (CINV), radiation-induced emesis (RIS), and postoperative nausea/vomiting (PONV).},
	issn = {2224-5839},	url = {https://apm.amegroups.org/article/view/1037}
}