%0 Journal Article
%T 5-HT3 receptor antagonists for the treatment of nausea/vomiting
%A Smith, Howard S.
%A Cox, Lorraine R.
%A Smith, Eric J.
%J Annals of Palliative Medicine
%D 2012
%B 2012
%9 
%! 5-HT3 receptor antagonists for the treatment of nausea/vomiting
%K 
%X It is well appreciated that a number of things (e.g., various insults, chemotherapeutic agents, radiation) may lead to the release of serotonin from the enterochromaffin of the gastrointestinal tract. Released serotonin may then bind to certain 5-HT3 receptors and promote nausea/vomiting. 5-HT3 receptor antagonists may ameliorate nausea/vomiting in a number of circumstances and have been utilized as important antiemetics for multiple conditions such as chemotherapy-induced nausea/vomiting (CINV), radiation-induced emesis (RIS), and postoperative nausea/vomiting (PONV).
%U https://apm.amegroups.org/article/view/1037
%V 1
%N 2
%P 115-120
%@ 2224-5839