TY  - JOUR
AU  - Smith, Howard S.
AU  - Cox, Lorraine R.
AU  - Smith, Eric J.
PY  - 2012
TI  - 5-HT3 receptor antagonists for the treatment of nausea/vomiting
JF  - Annals of Palliative Medicine; Vol 1, No 2 (July 14, 2012): Annals of Palliative Medicine
Y2  - 2012
KW  - 
N2  - It is well appreciated that a number of things (e.g., various insults, chemotherapeutic agents, radiation) may lead to the release of serotonin from the enterochromaffin of the gastrointestinal tract. Released serotonin may then bind to certain 5-HT3 receptors and promote nausea/vomiting. 5-HT3 receptor antagonists may ameliorate nausea/vomiting in a number of circumstances and have been utilized as important antiemetics for multiple conditions such as chemotherapy-induced nausea/vomiting (CINV), radiation-induced emesis (RIS), and postoperative nausea/vomiting (PONV).
UR  - https://apm.amegroups.org/article/view/1037