TY  - JOUR
AU  - Chan, Stephanie
AU  - Zhang, Liying
AU  - Rowbottom, Leigha
AU  - McDonald, Rachel
AU  - Bjarnason, Georg A.
AU  - Tsao, May
AU  - Barnes, Elizabeth
AU  - Danjoux, Cyril
AU  - Popovic, Marko
AU  - Lam, Henry
AU  - DeAngelis, Carlo
AU  - Chow, Edward
PY  - 2016
TI  - Effects of circadian rhythms and treatment times on the response of radiotherapy for painful bone metastases
JF  - Annals of Palliative Medicine; Vol 6, No 1 (January 20, 2017): Annals of Palliative Medicine
Y2  - 2016
KW  - 
N2  - Background: Previous studies have observed how the time of radiotherapy delivery can impact toxicities and outcomes. The goal of this study was to determine whether treatment time influenced radiotherapy response for bone metastases.  Methods: Patients who received radiation treatment to painful bone metastases from January 2000 to December 2010 were included in our analysis. Demographic and treatment information including performance status, primary site, treatment dose and fraction, and response were collected prospectively. Treatment times were extracted from patient medical records. Patients were allocated to 8:00 AM–11:00 AM, 11:01 AM–2:00 PM, or 2:01 PM–5:00 PM cohorts based on their treatment times. To compare treatment response between the three cohorts, the Fisher exact test was used. A two-sided P value of 
UR  - https://apm.amegroups.org/article/view/11983