TY  - JOUR
AU  - Mendez, Lucas C.
AU  - Raman, Srinivas
AU  - Wan, Bo Angela
AU  - da Silva, José Luiz Padilha
AU  - Moraes, Fábio Y.
AU  - Lima, Kennya M. L. B.
AU  - Silva, Maurício F.
AU  - Diz, Maria Del Pilar Estevez
AU  - Chow, Edward
AU  - Marta, Gustavo Nader
PY  - 2017
TI  - Quality of life in responders after palliative radiation therapy for painful bone metastases using EORTC QLQ-C30 and EORTC QLQ-BM22: results of a Brazilian cohort
JF  - Annals of Palliative Medicine; Vol 6, Supplement 1 (August 31, 2017): Annals of Palliative Medicine1
Y2  - 2017
KW  - 
N2  - Background: Bone metastases cause pain, suffering and impaired quality of life (QoL). Palliative radiotherapy (RT) and/or chemotherapy are effective methods in controlling pain, reducing analgesics use and improving QoL. This study goal was to investigate the changes in QoL scores among patients who responded to palliative treatment.   Methods: A prospective study evaluating the role of radiation therapy in a public academic hospital in São Paulo-Brazil recorded patients’ opioid use, pain score, Portuguese version of QLQ-BM22 and QLQ-C30 before and 2 months after radiotherapy. Analgesic use and pain score were used to calculate international pain response category. Overall response was defined as the sum of complete response (CR) and partial response (PR). CR was defined as pain score of 0 with no increase in analgesic intake whereas PR was defined as pain reduction ≥2 without analgesic increase or analgesic reduction in ≥25% without increase in pain at the treated site.   Results: From September 2014 to October 2015, 25 patients with bone metastases responded to RT or chemotherapy (1 CR, 24 PR). There were 8 male and 17 female patients. The median age of the 25 patients was 59 (range, 22 to 80) years old. Patient’s primary cancer site was breast [11], prostate [5], lung [2], others [7].   For QLQ-BM 22, the mean scores of 4 categories at baseline were: pain site (PS) 39, pain characteristics (PC) 61, function interference (FI) 49 and psycho-social aspects (PA) 57. At 2 month follow up, the scores were PS 27, PC 37, FI 70 and PA 59. Statistical significant improvement (P
UR  - https://apm.amegroups.org/article/view/14876