@article{APM3646,
author = {Evanthia Botsa and Sofia Mylona and Ioannis Koutsogiannis and Antonia Koundouraki and Loukas Thanos},
title = {CT image guided thermal ablation techniques for palliation of painful bone metastases},
journal = {Annals of Palliative Medicine},
volume = {3},
number = {2},
year = {2014},
keywords = {},
abstract = {Background: Many different treatment methods have been used for pain palliation in patients with bone metastases. The ideal treatment has to be fast, safe, effective and tolerable for the patient.
Objective: To evaluate the efficacy and safety of computed tomography (CT)-guided radiofrequency ablation (RFA) or microwave ablation (MWA) as a minimal invasive method of pain palliation.
Objective: Materials and methods: A total of forty-five patients with painful bone metastases were included in our study (median age 65.43; range, 36-90 years). Thirty patients were treated with RFA and fifteen with MWA, all under CT guidance. Lesion diameter was between 2 and 9 cm (mean ± SD: 3.9±2.6 cm). Pain was assessed in all patients with the Brief Pain Inventory (BPI). All procedures were performed under conscious sedation. RFAs were performed with a RITA Model 1500® electrosurgical generator with a seven or a nine-array multitined electrode depending on the lesion’s size. MWAs were done with AMICA-GEM microwave generator 2,450 MHz connected to a 14- or 16-gauge coaxial antenna. Technically successful ablation was considered to be when lesions were treated according to protocol and completely covered. After each session a dual-phase spiral CT examination with intravenous contrast medium was performed in order to evaluate immediate response. Patients were hospitalised and observed for 24-hour monitoring. Post-ablation assessment with BPI score and report of the use of analgesics was performed with telephone interview one, four and eight weeks after the ablation.
Results: In both groups there was a significant and similar decrease in the mean past day BPI score for worst pain, for average pain and for pain interference during daily life in comparison to preprocedural symptoms (P},
issn = {2224-5839}, url = {https://apm.amegroups.org/article/view/3646}
}