@article{APM8458,
author = {Ronald Chow and May Tsao and Natalie Pulenzas and Liying Zhang and Arjun Sahgal and David Cella and Hany Soliman and Cyril Danjoux and Carlo DeAngelis and Sherlyn Vuong and Edward Chow},
title = {Do patients with brain metastases selected for whole brain radiotherapy have worse baseline quality of life as compared to those for radiosurgery or neurosurgery (with or without whole brain radiotherapy)?},
journal = {Annals of Palliative Medicine},
volume = {5},
number = {1},
year = {2015},
keywords = {},
abstract = {Background: The purpose was to examine the baseline characteristics, symptoms and quality of life (QOL) in patients who receive different treatments for brain metastases.
Methods: Eligible patients were divided and analysed based on their treatment: whole brain radiotherapy (WBRT) alone versus stereotactic radiosurgery (SRS) or neurosurgery with or without WBRT. The Functional Assessment of Cancer Therapy-Brain (FACT-Br) items were grouped according to different domains for summary scores. The domains used for summary scores were physical, social/family, emotional, functional well-being (FWB) and additional concerns.
Results: A total of 120 patients were enrolled, with 37 treated with WBRT alone and 83 with SRS or neurosurgery with or without WBRT. Of the 50 baseline FACT-Br items, only five items (I feel ill; I get support from my friends; I worry about dying; I have difficulty expressing my thoughts, I am able to put my thoughts into action) were statistically worse in patients treated with WBRT alone (P},
issn = {2224-5839}, url = {https://apm.amegroups.org/article/view/8458}
}