Clarification of issues raised by our readers for the meta-analysis of the efficacy of aerobic exercise combined with resistance training on maintenance hemodialysis patients

In response to your questions in (1) for our meta-analysis (2), we have carefully checked the literature search process and data extraction process, and it may be due to lack of skill, and there are indeed problems with a small part of the data.

For the first question, because of the differences in search terms, there may indeed be studies missing.

For the second question. First, we believe that walking and walking in daily life belong to aerobic exercise; secondly, although the purpose of this paper is to evaluate the application value of aerobic exercise combined with resistance training in maintenance hemodialysis (MHD) patients, resistance exercise is dominant. In conclusion, we included the two studies of Abreu et al. (3) and Dong et al. (4) in this meta-analysis.

For the third question, the authors were not skilled enough for the data processing, resulting in glitches in the data extraction, and we will pay more attention to it in the future research.

Thanks to the readers for their careful reading and the discovery of the problem, we are deeply aware of the mistakes of this research and sincerely apologize to all readers.

Acknowledgments

Funding: None.

Footnote

Provenance and Peer Review: This article was commissioned by the editorial office, Annals of Palliative Medicine. The article did not undergo external peer review.

Conflicts of Interest: All authors have completed the ICMJE uniform disclosure form (available at https://apm.amegroups.com/article/view/10.21037/apm-2022-03/coif). The authors have no conflicts of interest to declare.

Ethical Statement: The authors are accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0/.

References

1. Zhang H, Zhang F. Results of meta-analysis should be interpreted with caution. Ann Palliat Med 2022; [Crossref] [PubMed]
2. Cai X, Zeng D, Deng J. A systematic review and meta-analysis of the efficacy of aerobic exercise combined with resistance training on maintenance hemodialysis patients. Ann Palliat Med 2022;11:1360-8. [Crossref] [PubMed]
3. Abreu CC, Cardozo LFMF, Stockler-Pinto MB, et al. Does resistance exercise performed during dialysis modulate Nrf2 and NF-κB in patients with chronic kidney disease? Life Sci 2017;188:192-7. [Crossref] [PubMed]
4. Dong ZJ, Zhang HL, Yin LX. Effects of intradialytic resistance exercise on systemic inflammation in maintenance hemodialysis patients with sarcopenia: a randomized controlled trial. Int Urol Nephrol 2019;51:1415-24. [Crossref] [PubMed]